La Altagracia is the easternmost province of the country and is also the most famous in the world, hosting Punta Cana and Bavaro, two all-included tourist resorts. Located along the long beaches of white sand lined with palm trees, they are a paradise for vacationers. The main city of Higüey is the entrance to the province. The city is a center of pilgrimage celebrating the Virgin Altagracia, patroness of the country. Each January 21, the pilgrims celebrate the Holy Virgin in the Basilica of original and imposing architecture.

At the southern end of the province is one of the richest reserves of the country, the Eastern National Park. This is an area of nearly 42 hectares, to which Saona Island is incorporated, a small island of 130 hectares with pristine beaches and crystal clear and breathtaking waters. The park is the largest archaeological park expressing the Taino civilization. Fauna and flora are protected ; you can see many bird species, including eleven endemic ones, dolphins, manatees ... The marine species are very diversified offering a beautiful diving spot for exploration. At the exit of the park, you reach the fishing village of Bayahibe. Tourist resorts have opened in recent years and disturbed the tranquility of the place.

The province of La Romana is smaller than the previous one, but doesn’t lack of interest. The city of La Romana was founded in 1502. Its development was strong in the early 20th century with the construction of the largest private sugar refinery in the Dominican Republic. The hinterland is rich in agricultural production of sugar cane, mainly.

Tourism took over later on with a lot of luxury projects such as Casa de Campo. A few kilometers from the city dominates a quite original village built in 1976, Los Altos de Chavón. It is a replication of an Italian village from the 16th century. It houses a cultural foundation, which trains Dominicans in graphic arts, a gallery, a museum of pre-Columbian archeology and a concert hall.

Part of this region is rich in caves that have preserved traces of the past, such as the Cave of Wonders, "la cueva de las maravillas", near San Pedro de Marcoris, between the rivers Soco and Cumayasa ; it is a geological formation with impressive stalactites and stalagmites. Along the path of 240 meters at 25 meters deep, nearly 500 pre-Columbian pictograms can be seen on the walls.

San Pedro de Marcoris is one of the largest cities in the country, which provides an opening to the ocean for shipping hinterland agricultural production. It is also an important university center.

The north of the eastern part is mainly agricultural. Santa Cruz del Seibo is the capital of the province of El Seibo. Bulls are released during the celebrations of the city. Tourism is very poorly developed, with the exception of few projects on the coast.